Endocrine Abstracts

Aim: Differentiated thyroid cancer (DTC) is the most commonly seen endocrinological tumour. During the follow up of DTC, serum thyroglobulin (TG) levels, neck ultrasound, fine needle aspiration biopsy (FNAB) of the suspicious lymph nodes are important tools. TG washout of the suspicious lymph node as well as the FNAB can detect metastasis and recurrences earlier. In this study we aimed to show the diagnostic role of TG washout of suspicious lymph node FNAB which is not routine...

Introduction: We investigated the levels of IGF1 in acute myocardial infarction (AMI) and sought to determine whether a decrease might influence the long-term prognosis.Material and methods: Sixty-five patients who were admitted to our hospital with AMI were included in the study along with 26 other patients without coronary artery disease (CAD) who served as the control group. Fasting blood samples of all of the patients with AMI were obtained at the ho...

Introduction: Fat mass and obesity associated (FTO) gene was the first susceptibility locus for obesity identified by genome wide association studies. The association of the FTO gene with obesity and metabolic syndrome is conflicting in both adults and adolescents. The aim of this study was to examine the role of the FTO gene variant rs9939609 as a candidate gene for obesity and metabolic syndrome, among Caucasian adolescents in South-eastern Turkey.Meth...

Introduction: Thyroid gland is susceptible for nodulation. It is not clear which mechanism is responsible for the growth of only some follicular cells resulting in nodule formation. Selenium deficiency may a risk factor in the development of thyroid nodules. The aim of this study was to investigate the relationship between selenium levels in patients with euthyroid nodular thyroid diseases.Design: Euthyroid 70 patients with solitary thyroid nodule, euthy...

Introduction: Subacute thyroiditis due to vaccination is reported in only a few case reports. A peritoneal dialysis patient who experienced a repeating attack after a vaccination for influenzae while she was being followed and treated successfully for subacute thyroiditis is presented.Case: A 28-year-old female patient who has been applying dialysis for nine years was seen in policlinic telling about upper respiratory tract infection 2 months ago and pai...

Hemoglobin A1c (HbA1c) has been used as a clinically significant evaluation tool for analyses regarding glycemic control. Guidelines recommend patients with type 2 diabetes mellitus (T2DM) should aim for an A1C≤7.0%, but real world data is limited in the elderly regarding outcomes associated with different A1C levels.A thousand six hundred Turkish cases were enrolled in this study. The mean age of the patients was 57 (17 to 91) years. The mean HbA1...

Introduction: The prevalence of primary adrenal insufficiency (Addison disease; AD) in pregnancy is unknown. Female patients with adrenal insufficiency are usually infertile and once get pregnant are at increased risk for preterm deliveries, Cesarean section and babies with low birth weights. Recognition of AD during pregnancy may be difficult as many of the clinical complaints like weakness, lightheadness, syncope, nausea, vomiting, hyponatremia, and increased pigmentation ca...

Introduction: Manifestations of MEN2B include medullary carcinoma of thyroid (MCT), pheochromocytoma, and a number of somatic mutations like marfanoid habitus, mucosal neuromas, ganglioneuromatosis of the bowel. Dural ectasia results from enlargement of the spinal canal, was identified in 63–92% of patients with Marfan syndrome, however, it was not previously described in MEN2B. We detected dural ectasia in our patient with MEN2B.Case report: A 28 y...

A 39-year-old lady presented with chest infection and was found to be hyponatraemic (114 mmol/l) during her third pregnancy. Short synacthen test (SST) revealed inappropriately low ACTH (39 ng/l) with adrenocortical failure (cortical 163, 355, 503 at 0, 30 and 60 min respectively). She was started on replacement hydrocortisone. Adrenal autoantibodies were negative. Other tests showed IGF-1 14.8 (13–50 ηmol/l), growth hormone <0.1 (<10 mU/l), prolactin 677 (&#...

Introduction: Subacute thyroiditis (SAT) can often resolve completely; however, it has been observed that in 11.6% of patients, permanent hypothyroidism (PHT) may develop the follow-up after diagnosis. Various studies have explored the relationship between thyroid volume at the time of diagnosis, post-treatment changes in thyroid volume, steroid therapy, and the development of PHT following SAT. While some studies suggest associations, there are also data indicating that no si...